Pancreatic Islet Beta Cell Protective Effect of Oral Vanadyl Sulphate in Streptozotocin-induced Diabetic Rats, an Ultrastructure Study
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چکیده
منابع مشابه
HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF PANCREATIC ISLET BETA CELLS OF DIABETIC RATS TREATED WITH ORAL VANADYL SULPHATE
Vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. The aim of the present study was to clarify histological and immunohistochemical changes that occur in the pancreatic beta (β) cells of vanadyl sulphate (VS)-treated streptozotocin (STZ) induced diabetic rats. Male Wi star rats were made diabetic by injecting a single intravenous dose of STZ (...
متن کاملimmunohistochemical study of the pancreatic islet beta cells of diabetic rats treated with oral vanadyl sulphate
introduction: vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. the aim of the present study was to clarify immunohistochemical changes that occur in the pancreatic beta ([pancreatic islet beta]) cells of vanadyl sulphate (vs) treated stz induced diabetic rats. materials and methods: male wistar rats were made diabetic with injecting a single intr...
متن کاملhistological and immunohistochemical study of pancreatic islet beta cells of diabetic rats treated with oral vanadyl sulphate
vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. the aim of the present study was to clarify histological and immunohistochemical changes that occur in the pancreatic beta (β) cells of vanadyl sulphate (vs)-treated streptozotocin (stz) induced diabetic rats. male wi star rats were made diabetic by injecting a single intravenous dose of stz (40 mg...
متن کاملQuantitative Assessment of Proliferative Effects of Oral Vanadium on Pancreatic Islet Volumes and Beta Cell Numbers of Diabetic Rats
Background: Oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. Soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. Methods: Adult male Sprague-Dawley rats were made diabetic with intravenous s...
متن کاملTrophic actions of oral vanadium and improved glycemia on the pancreatic beta-cell ultrastructure of streptozotocin-induced diabetic rats.
CONTEXT Oral vanadyl sulfate (vanadium) has potent hypoglycemic effects in diabetes animals, but data about its actions on pancreatic beta-cells (BC) ultrastructure is limited. OBJECTIVE Partial diabetic rats were treated with vanadium and insulin injection and their effects on BC ultrastructure are studied. METHODS Male rats were made diabetic with intravenous streptozotocin injection (STZ...
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ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2010
ISSN: 1028-8880
DOI: 10.3923/pjbs.2010.1135.1140